Rapamycin conditioning of dendritic cells differentiated from human ES cells promotes a tolerogenic phenotype.
While human embryonic stem cells (hESCs) may one day facilitate the treatment of degenerative diseases requiring cell replacement therapy, the success of regenerative medicine is predicated on overcoming the rejection of replacement tissues. Given the role played by dendritic cells (DCs) in the esta...
المؤلفون الرئيسيون: | Silk, K, Leishman, A, Nishimoto, K, Reddy, A, Fairchild, P |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2012
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مواد مشابهة
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Directed Differentiation of Human Induced Pluripotent Stem Cells into Dendritic Cells Displaying Tolerogenic Properties and Resembling the CD141+ Subset
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Tolerogenicity is not an absolute property of a dendritic cell.
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