Assessing the role of ADAM10 in Trastuzumab treatment and resistance

Assessing the role of ADAM10 in Trastuzumab treatment and resistance

<p>Overexpression of the HER2 receptor occurs in about 15-20% of all breast cancers and is correlated with poor prognosis. Trastuzumab (Herceptin®), a monoclonal antibody targeting HER2, was shown to prolong survival of these patients. However, primary or acquired resistance remains a drawback...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoir:	Feldinger, K
Rannpháirtithe:	Kong, A
Formáid:	Tráchtas
Teanga:	English
Foilsithe / Cruthaithe:	2012
Ábhair:	Cell Biology (see also Plant sciences) Oncology Biology

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