Monocyte trafficking to hepatic sites of bacterial infection is chemokine independent and directed by focal intercellular adhesion molecule-1 expression.

Recruitment of CCR2(+)Ly6C(high) monocytes to sites of infection is essential for efficient clearance of microbial pathogens. Although CCR2-mediated signals promote monocyte emigration from bone marrow, the contribution of CCR2 to later stages of monocyte recruitment remains unresolved. In this arti...

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Bibliographic Details
Main Authors: Shi, C, Velázquez, P, Hohl, T, Leiner, I, Dustin, M, Pamer, E
Format: Journal article
Language:English
Published: 2010