Multidimensional endotyping in patients with severe asthma reveals inflammatory heterogeneity in matrix metalloproteinases and chitinase 3–like protein 1

Disease heterogeneity in patients with severe asthma and its relationship to inflammatory mechanisms remain poorly understood.We aimed to identify and replicate clinicopathologic endotypes based on analysis of blood and sputum parameters in asthmatic patients.One hundred ninety-four asthmatic patien...

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Bibliographic Details
Main Authors: Hinks, T, Brown, T, Lau, L, Rupani, H, Barber, C, Elliott, S, Ward, J, Ono, J, Ohta, S, Izuhara, K, Djukanović, R, Kurukulaaratchy, R, Chauhan, A, Howarth, P
Format: Journal article
Language:English
Published: Elsevier 2016