Quantitative imaging of endosome acidification and single retrovirus fusion with distinct pools of early endosomes.

Diverse enveloped viruses enter host cells through endocytosis and fuse with endosomal membranes upon encountering acidic pH. Currently, the pH dynamics in virus-carrying endosomes and the relationship between acidification and viral fusion are poorly characterized. Here, we examined the entry of av...

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Bibliographic Details
Main Authors: Padilla-Parra, S, Matos, P, Kondo, N, Marin, M, Santos, N, Melikyan, G
Format: Journal article
Language:English
Published: 2012