Redesign of ultrasensitive and robust RecA gene circuit to sense DNA damage
SOS box of the recA promoter, PVRecA from Vibrio natriegens was characterized, cloned and expressed in a probiotic strain E. coli Nissle 1917. This promoter was then rationally engineered according to predicted interactions between LexA repressor and PVRecA. The redesigned PVRecA‐AT promoter showed...
| Glavni autori: | , , , , , |
|---|---|
| Format: | Journal article |
| Jezik: | English |
| Izdano: |
Wiley
2021
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