Targeting the Ras superfamily via their regulatory GEF complexes

<p>The Ras superfamily of small GTPases are guanine nucleotide-dependent molecular switches which are involved in numerous signalling pathways in the cell. Mutations or dysregulation of these proteins are associated with a variety of diseases, and so the small GTPases are important targets in...

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Bibliographic Details
Main Author: Gray, J
Other Authors: Brennan, P
Format: Thesis
Language:English
Published: 2021
Subjects: