Targeting the Ras superfamily via their regulatory GEF complexes

<p>The Ras superfamily of small GTPases are guanine nucleotide-dependent molecular switches which are involved in numerous signalling pathways in the cell. Mutations or dysregulation of these proteins are associated with a variety of diseases, and so the small GTPases are important targets in...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur: Gray, J
Awduron Eraill: Brennan, P
Fformat: Traethawd Ymchwil
Iaith:English
Cyhoeddwyd: 2021
Pynciau: