Targeting the Ras superfamily via their regulatory GEF complexes

<p>The Ras superfamily of small GTPases are guanine nucleotide-dependent molecular switches which are involved in numerous signalling pathways in the cell. Mutations or dysregulation of these proteins are associated with a variety of diseases, and so the small GTPases are important targets in...

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Détails bibliographiques
Auteur principal: Gray, J
Autres auteurs: Brennan, P
Format: Thèse
Langue:English
Publié: 2021
Sujets: