Targeting the Ras superfamily via their regulatory GEF complexes
<p>The Ras superfamily of small GTPases are guanine nucleotide-dependent molecular switches which are involved in numerous signalling pathways in the cell. Mutations or dysregulation of these proteins are associated with a variety of diseases, and so the small GTPases are important targets in...
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| 格式: | Thesis |
| 語言: | English |
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2021
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