Down-regulation of the forkhead transcription factor Foxp1 is required for monocyte differentiation and macrophage function.

Down-regulation of the forkhead transcription factor Foxp1 by integrin engagement controls monocyte differentiation in vitro. To determine whether Foxp1 plays a critical role in monocyte differentiation and macrophage functions in vivo, we generated transgenic mice (macFoxp1tg) overexpressing human...

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Bibliographic Details
Main Authors: Shi, C, Sakuma, M, Mooroka, T, Liscoe, A, Gao, H, Croce, K, Sharma, A, Kaplan, D, Greaves, D, Wang, Y, Simon, D
Format: Journal article
Language:English
Published: 2008