Comparative heterochromatin profiling reveals conserved and unique epigenome signatures linked to adaptation and development of malaria parasites

Heterochromatin-dependent gene silencing is central to the adaptation and survival of Plasmodium falciparum malaria parasites, allowing clonally variant gene expression during blood infection in humans. By assessing genome-wide heterochromatin protein 1 (HP1) occupancy, we present a comprehensive an...

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Bibliographic Details
Main Authors: Fraschka, SA, Filarsky, M, Hoo, R, Niederwieser, I, Yam, XY, Brancucci, NMB, Mohring, F, Mushunje, AT, Huang, X, Christensen, PR, Nosten, F, Bozdech, Z, Russell, B, Moon, RW, Marti, M, Preiser, PR, Bártfai, R, Voss, TS
Format: Journal article
Language:English
Published: Elsevier 2018