Enhanced tumor uptake and penetration of virotherapy using polymer stealthing and focused ultrasound.

BACKGROUND: Oncolytic viruses are among the most powerful and selective cancer therapeutics under development and are showing robust activity in clinical trials, particularly when administered directly into tumor nodules. However, their intravenous administration to treat metastatic disease has been...

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Bibliographic Details
Main Authors: Carlisle, R, Choi, J, Bazan-Peregrino, M, Laga, R, Subr, V, Kostka, L, Ulbrich, K, Coussios, C, Seymour, L
Format: Journal article
Language:English
Published: Oxford University Press 2013