Bifunctional iminophosphorane catalyzed amide enolization for enantioselective cyclohexadienone desymmetrization.

The organocatalytic enolization of 2-arylacetamides, followed by an enantioselective intramolecular conjugate addition to tethered 2,5-cyclohexadienones, yielding 3D fused N-heterocycles, is described. The transformation represents the first strong activating group-free activation of carboxamides vi...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Poh, CYX, Rozsar, D, Yang, J, Christensen, KE, Dixon, DJ
التنسيق: Journal article
اللغة:English
منشور في: Wiley 2023