Bifunctional iminophosphorane catalyzed amide enolization for enantioselective cyclohexadienone desymmetrization.
The organocatalytic enolization of 2-arylacetamides, followed by an enantioselective intramolecular conjugate addition to tethered 2,5-cyclohexadienones, yielding 3D fused N-heterocycles, is described. The transformation represents the first strong activating group-free activation of carboxamides vi...
Κύριοι συγγραφείς: | Poh, CYX, Rozsar, D, Yang, J, Christensen, KE, Dixon, DJ |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
Wiley
2023
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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