Sickle cell trait and the risk of Plasmodium falciparum malaria and other childhood diseases

Background: The gene for sickle hemoglobin (Hbs) is a prime example of natural selection. It is generally believed that its current prevalence in many tropical populations reflects selection for the carrier form (sickle cell trait [HbAS]) through a survival advantage against death from malaria. Neve...

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Bibliographic Details
Main Authors: Williams, T, Mwangi, T, Wambua, S, Alexander, N, Kortok, M, Snow, R, Marsh, K
Other Authors: Infectious Diseases Society of America
Format: Journal article
Language:English
Published: University of Chicago Press 2005
Subjects: