Ras as a target in cancer therapy.
Ras proteins are guanine nucleotide-binding proteins that are central to the control of normal and transformed cell growth and that are mutated in approximately 30% of human cancers. Binding of ligands to various growth factor receptors activates Ras and subsequently a plethora of downstream effecto...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2002
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