Hypoxia inducible factors 1alpha and 2alpha are associated with VEGF expression and angiogenesis in gallbladder carcinomas.

AIMS: To investigate the significance of the hypoxia inducible factors HIF-1alpha and HIF-2alpha in gallbladder adenocarcinomas and their relation to angiogenesis and to the expression of VEGF, an angiogenic factor transcriptionally regulated by HIFalphas. METHODS: HIF-1alpha and 2alpha expression w...

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Bibliographic Details
Main Authors: Giatromanolaki, A, Sivridis, E, Simopoulos, C, Polychronidis, A, Gatter, K, Harris, A, Koukourakis, M
Format: Journal article
Language:English
Published: 2006