Sustained MAPK/ERK activation in adult Schwann cells impairs nerve repair
The MAPK/ERK pathway has a critical role in PNS development. It is required for Schwann cell (SC) differentiation and myelination; sustained embryonic MAPK/ERK activation in SCs enhances myelin growth overcoming signals that normally end myelination. Excess activation of this pathway can be maladapt...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Published: |
Society for Neuroscience
2017
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