Factor I autoantibodies in patients with atypical hemolytic uremic syndrome: disease-associated or an epiphenomenon?

Factor I autoantibodies in patients with atypical hemolytic uremic syndrome: disease-associated or an epiphenomenon?

BACKGROUND AND OBJECTIVES: Atypical hemolytic uremic syndrome is a disease associated with mutations in the genes encoding the complement regulators factors H and I. In addition, factor H autoantibodies have been reported in ∼10% of patients with atypical hemolytic uremic syndrome. This study searc...

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Bibliographic Details
Main Authors: Kavanagh, D, Pappworth, I, Anderson, H, Hayes, C, Moore, I, Hunze, E, Bennaceur, K, Roversi, P, Lea, S, Strain, L, Ward, R, Plant, N, Nailescu, C, Goodship, T, Marchbank, K
Format: Journal article
Language:English
Published: 2012

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