Dystrophin Threshold Level Necessary for Normalization of Neuronal Nitric Oxide Synthase, Inducible Nitric Oxide Synthase, and Ryanodine Receptor-Calcium Release Channel Type 1 Nitrosylation in Golden Retriever Muscular Dystrophy Dystrophinopathy

At present, the clinically most advanced strategy to treat Duchenne muscular dystrophy (DMD) is the exon-skipping strategy. Whereas antisense oligonucleotide-based clinical trials are underway for DMD, it is essential to determine the dystrophin restoration threshold needed to ensure improvement of...

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Bibliographic Details
Main Authors: Gentil, C, Le Guiner, C, Falcone, S, Hogrel, J-V, Peccate, C, Lorain, S, Benkhelifa-Ziyyat, S, Guigand, L, Montus, M, Servais, L, Voit, T, Piétri-Rouxel, F
Format: Journal article
Language:English
Published: Mary Ann Liebert 2016