HLA-B27

Possession of the human leukocyte antigen (HLA) class I molecule B27 is strongly associated with ankylosing spondylitis (AS), but the pathogenic role of HLA-B27 is unknown. Two broad theories most likely explain the role of HLA-B27 in AS pathogenesis. The first is based on the natural immunological...

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Bibliographic Details
Main Author: Bowness, P
Format: Journal article
Language:English
Published: Annual Reviews 2015