Specific proliferative T cell responses and antibodies elicited by vaccination with simian immunodeficiency virus Nef do not confer protection against virus challenge.

The efficacy of immunizing with a combination of simian immunodeficiency virus (SIV) Nef vaccines was evaluated. Four vaccinates received three intradermal immunizations with recombinant vaccinia virus that expressed SIV Nef, followed by three intramuscular immunizations with rDNA also expressing SI...

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Bibliographic Details
Main Authors: Wade-Evans, A, Stott, J, Hanke, T, Stebbings, R, Berry, N, Lines, J, Sangster, R, Silvera, P, Walker, B, MacManus, S, Davis, G, Cowie, J, Arnold, C, Hull, R, Almond, N
Format: Journal article
Language:English
Published: 2001