A CRISPR endonuclease gene drive reveals distinct mechanisms of inheritance bias
CRISPR/Cas gene drives can bias transgene inheritance through different mechanisms. Homing drives are designed to replace a wild-type allele with a copy of a drive element on the homologous chromosome. In <em>Aedes aegypti</em>, the sex-determining locus is closely linked to the white ge...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Springer Nature
2022
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