Efficacy of a series of alpha-pyrone derivatives against Leishmania (L.) infantum and Trypanosoma cruzi

The neglected tropical diseases Chagas disease and leishmaniasis affect together more than 20 million people living mainly in developing countries. The mainstay of treatment is chemotherapy, however the drugs of choice, which include benznidazole and miltefosine, are toxic and have numerous side eff...

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Bibliographic Details
Main Authors: Tempone, A, Ferreira, D, Lima, M, Costa Silva, T, Borborema, S, Reimão, J, Galuppo, M, Guerra, J, Russell, A, Wynne, G, Lai, R, Cadelis, M, Copp, B
Format: Journal article
Language:English
Published: Elsevier 2017