Metabolic adaptations in cancers expressing isocitrate dehydrogenase mutations
<p>The most frequently mutated metabolic genes in human cancer are those encoding the enzymes isocitrate dehydrogenase 1 (IDH1) and IDH2; these mutations have so far been identified in more than 20 tumor types. Since <em>IDH</em> mutations were first reported in g...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Cell Press
2021
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