The structure of HIV-1 Rev filaments suggests a bilateral model for Rev-RRE assembly.

HIV-1 Rev protein mediates the nuclear export of viral RNA genomes. To do so, Rev oligomerizes cooperatively onto an RNA motif, the Rev-response element (RRE), forming a complex that engages with the host nuclear export machinery. To better understand Rev oligomeri...

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Váldodahkkit: DiMattia, M, Watts, N, Cheng, N, Huang, R, Heymann, J, Grimes, J, Wingfield, P, Stuart, D, Steven, A
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: Elsevier 2016