The structure of HIV-1 Rev filaments suggests a bilateral model for Rev-RRE assembly.
HIV-1 Rev protein mediates the nuclear export of viral RNA genomes. To do so, Rev oligomerizes cooperatively onto an RNA motif, the Rev-response element (RRE), forming a complex that engages with the host nuclear export machinery. To better understand Rev oligomeri...
Hoofdauteurs: | DiMattia, M, Watts, N, Cheng, N, Huang, R, Heymann, J, Grimes, J, Wingfield, P, Stuart, D, Steven, A |
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Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
Elsevier
2016
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