The structure of HIV-1 Rev filaments suggests a bilateral model for Rev-RRE assembly.
HIV-1 Rev protein mediates the nuclear export of viral RNA genomes. To do so, Rev oligomerizes cooperatively onto an RNA motif, the Rev-response element (RRE), forming a complex that engages with the host nuclear export machinery. To better understand Rev oligomeri...
| Main Authors: | , , , , , , , , |
|---|---|
| 格式: | Journal article |
| 语言: | English |
| 出版: |
Elsevier
2016
|