A loss of host-derived MMP-7 promotes myeloma growth and osteolytic bone disease in vivo
Matrix metalloproteinases (MMPs) play a critical role in cancer pathogenesis, including tumor growth and osteolysis within the bone marrow microenvironment. However, the anti-tumor effects of MMPs are poorly understood, yet have significant implications for the therapeutic potential of targeting MMP...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Springer Verlag
2017
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