A loss of host-derived MMP-7 promotes myeloma growth and osteolytic bone disease in vivo

Matrix metalloproteinases (MMPs) play a critical role in cancer pathogenesis, including tumor growth and osteolysis within the bone marrow microenvironment. However, the anti-tumor effects of MMPs are poorly understood, yet have significant implications for the therapeutic potential of targeting MMP...

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Bibliographic Details
Main Authors: Lwin, S, Fowler, J, Drake, M, Edwards, J, Lynch, C, Edwards, C
Format: Journal article
Language:English
Published: Springer Verlag 2017