Ionic current enhancement through localised membrane geometrical deformation

Bleb-inducing aspiration in a patch-clamp has previously been proposed as a controlled proxy for ion channel damage characterisation in brain trauma. Under increasing pressure, voltage gated sodium channels Na1.6 have been observed to exhibit an altered dynamics known as “left-shift”. While many num...

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Bibliographic Details
Main Authors: Jerusalem, A, Kwong, A
Format: Journal article
Published: Elsevier 2019