Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters.
Transcriptional termination by RNA polymerase II at the 3' end of genes encoding poly(A)+ mRNAs is thought to require two distinct cis-active elements: a functional poly(A) signal and a downstream transcriptional pause site. An important requirement for efficient termination is to prevent trans...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1993
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