The requirement for endothelial cell tetrahydrobiopterin in health and disease
<p>Tetrahydrobiopterin (BH4) is an essential cofactor for endothelial nitric oxide synthase (eNOS) function and nitric oxide (NO) generation. Augmentation of BH4 levels can prevent eNOS uncoupling and improve endothelial dysfunction in vascular disease states. However, the physiological requir...
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| Format: | Thesis |
| Language: | English |
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2014
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