Investigating eukaryotic elongation factor 2 kinase/eukaryotic translation elongation factor 2 pathway regulation and its role in protein synthesis impairment during disuse-induced skeletal muscle atrophy
The principal mechanism underlying the reduced rate of protein synthesis in atrophied skeletal muscle is largely unknown. Eukaryotic elongation factor 2 kinase (eEF2k) impairs the ability of eukaryotic translation elongation factor 2 (eEF2) to bind to the ribosome via T56 phosphorylation. Perturbati...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Elsevier
2023
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