Dynamic lysine methylation on histone H3 defines the regulatory phase of gene transcription.

Covalent modifications to histones are key epigenetic marks that control gene transcription. Multiple lysine residues on histone H3 are methylated (me), but their functions are unclear. Here, we demonstrate two phases of combinatorial and dynamic H3 methylation during induction of transcription at M...

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Bibliographic Details
Main Authors: Morillon, A, Karabetsou, N, Nair, A, Mellor, J
Format: Journal article
Language:English
Published: 2005