Liver X receptors downregulate 11beta-hydroxysteroid dehydrogenase type 1 expression and activity.
11Beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD-1) converts inactive corticosteroids into biologically active corticosteroids, thereby regulating the local concentration of active glucocorticoids, such as cortisol. 11beta-HSD-1 is particularly expressed in adipocytes and liver and appears to...
Prif Awduron: | Stulnig, T, Oppermann, U, Steffensen, K, Schuster, G, Gustafsson, J |
---|---|
Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2002
|
Eitemau Tebyg
-
Role of type-1 11beta-hydroxysteroid dehydrogenase in detoxification processes.
gan: Maser, E, et al.
Cyhoeddwyd: (1997) -
Type 1 11beta-hydroxysteroid dehydrogenase as universal drug target in metabolic diseases?
gan: Oppermann, U
Cyhoeddwyd: (2006) -
Function, gene organization and protein structures of 11beta-hydroxysteroid dehydrogenase isoforms.
gan: Oppermann, U, et al.
Cyhoeddwyd: (1997) -
Cloning and primary structure of murine 11 beta-hydroxysteroid dehydrogenase/microsomal carbonyl reductase.
gan: Oppermann, U, et al.
Cyhoeddwyd: (1995) -
Structure and function of human 17beta-hydroxysteroid dehydrogenases.
gan: Lukacik, P, et al.
Cyhoeddwyd: (2006)