Regulation of MITF and Brn2 in melanoma

<p>Melanoma is the most aggressive skin cancer with high recurrence and low survival rate. In addition to genetic mechanisms, resistance also arises from phenotypic heterogeneity in which a proportion of cells, the so-called melanoma stem or initiating cells, survive therapy. Due to a lack of...

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Bibliographic Details
Main Author: Agkatsev, S
Other Authors: Seymour, L
Format: Thesis
Language:English
Published: 2014
Subjects: