Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor.
Expression of surface immunoglobulin appears critical for the growth and survival of B-cell lymphomas. In follicular lymphoma, we found previously that the Ig variable (V) regions in the B-cell receptor express a strikingly high incidence of N-glycosylation sequons, NX(S/T). These potential glycosyl...
Main Authors: | , , , , , , , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2007
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