Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor.
Expression of surface immunoglobulin appears critical for the growth and survival of B-cell lymphomas. In follicular lymphoma, we found previously that the Ig variable (V) regions in the B-cell receptor express a strikingly high incidence of N-glycosylation sequons, NX(S/T). These potential glycosyl...
Main Authors: | Radcliffe, C, Arnold, J, Suter, D, Wormald, M, Harvey, D, Royle, L, Mimura, Y, Kimura, Y, Sim, R, Inogès, S, Rodriguez-Calvillo, M, Zabalegui, N, de Cerio, A, Potter, K, Mockridge, C, Dwek, R, Bendandi, M, Rudd, P, Stevenson, F |
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Format: | Journal article |
Language: | English |
Published: |
2007
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