Genome-wide association between branch point properties and alternative splicing

The branch point (BP) is one of the three obligatory signals required for pre-mRNA splicing. In mammals, the degeneracy of the motif combined with the lack of a large set of experimentally verified BPs complicates the task of modeling it in silico, and therefore of predicting the location of natural...

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Bibliographic Details
Main Authors: Corvelo, A, Hallegger, M, Smith, C, Eyras, E
Format: Journal article
Language:English
Published: Public Library of Science 2010