SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells

During development, it is unclear if lineage-fated cells derive from multilineage-primed progenitors and whether active mechanisms operate to restrict cell fate. Here we investigate how mesoderm specifies into blood-fated cells. We document temporally restricted co-expression of blood (Scl/Tal1), ca...

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Bibliographic Details
Main Authors: Chagraoui, H, Kristiansen, MS, Ruiz, JP, Serra-Barros, A, Richter, J, Hall-Ponselé, E, Gray, N, Waithe, D, Clark, K, Hublitz, P, Repapi, E, Otto, G, Sopp, P, Taylor, S, Thongjuea, S, Vyas, P, Porcher, C
Format: Journal article
Language:English
Published: Springer Nature 2018