Indoleamine 2,3-dioxygenase: distribution and function in the developing human placenta.
Studies in mice have suggested that the placenta is protected from immune rejection by maternal T cells by means of localised indoleamine 2,3-dioxygenase dependent depletion of tryptophan. To determine whether such mechanisms might operate in the human placenta, we have studied the physiological imp...
Main Authors: | , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2004
|