Indoleamine 2,3-dioxygenase: distribution and function in the developing human placenta.

Studies in mice have suggested that the placenta is protected from immune rejection by maternal T cells by means of localised indoleamine 2,3-dioxygenase dependent depletion of tryptophan. To determine whether such mechanisms might operate in the human placenta, we have studied the physiological imp...

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Bibliographic Details
Main Authors: Kudo, Y, Boyd, C, Spyropoulou, I, Redman, C, Takikawa, O, Katsuki, T, Hara, T, Ohama, K, Sargent, I
Format: Journal article
Language:English
Published: 2004