The IMPDH cytoophidium couples metabolism and fetal development in mice

The cytoophidium is an evolutionarily conserved subcellular structure formed by filamentous polymers of metabolic enzymes. In vertebrates, inosine monophosphate dehydrogenase (IMPDH), which catalyses the rate-limiting step in guanosine triphosphate (GTP) biosynthesis, is one of the best-known cytoop...

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Bibliographic Details
Main Authors: Peng, M, Keppeke, GD, Tsai, L, Chang, C, Liu, J, Sung, L
Format: Journal article
Language:English
Published: Springer 2024