Osteoblasts protect multiple myeloma cells from T-cell-induced apoptosis

Osteoblasts protect multiple myeloma cells from T-cell-induced apoptosis

Xehetasun bibliografikoak
Egile Nagusiak:	Locklin, R, Russell, R, Croucher, P, Edwards, C
Formatua:	Conference item
Argitaratua:	2007

Antzeko izenburuak

Cells of the bone marrow microenvironment protect myeloma cells from apoptosis induced by TRAIL but not by agonists of TRAIL death receptors.
nork: Locklin, R, et al.
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Agonists of TRAIL death receptors induce myeloma cell apoptosis that is not prevented by cells of the bone marrow microenvironment.
nork: Locklin, R, et al.
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Lactoferrin protects osteoblasts and osteocytes from apoptosis
nork: Locklin, R, et al.
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Differential sensitivity of normal osteoblast-like cells and osteosarcoma cells to TRAIL and an agonist antibody to TRAIL receptor-2
nork: Locklin, R, et al.
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The potent bisphosphonate ibandronate does not induce myeloma cell apoptosis in a murine model of established multiple myeloma.
nork: Shipman, C, et al.
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Myeloma cells isolated from patients with multiple myeloma express osteoprotegerin ligand.
nork: Shipman, C, et al.
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Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti-tumour activity.
nork: Shipman, C, et al.
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Sulforaphane - A new therapy for mutliple myeloma?
nork: Locklin, R, et al.
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The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway.
nork: Shipman, C, et al.
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Myeloma cells decrease EphB4 expression in osteoblasts; A novel mechanism for regulation of bone formation in multiple myeloma
nork: Bates, A, et al.
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Myeloma cells decrease EphB4 expression in osteoblasts: A novel mechanism for regulation of bone formation in multiple myeloma
nork: Bates, A, et al.
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Selective targeting of death receptor 5 circumvents resistance of MG-63 osteosarcoma cells to TRAIL-induced apoptosis.
nork: Locklin, R, et al.
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Apomine, an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo.
nork: Edwards, C, et al.
Argitaratua: (2007)

Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.
nork: Zhigang Xie, et al.
Argitaratua: (2011-01-01)

N-cadherin-mediated interaction with multiple myeloma cells inhibits osteoblast differentiation
nork: Richard W.J. Groen, et al.
Argitaratua: (2011-11-01)

Tumor-host cell interactions in the bone disease of myeloma.
nork: Fowler, J, et al.
Argitaratua: (2011)

BIM is a novel regulator of glucocorticoid-induced apoptosis in osteoblasts
nork: Espina, B, et al.
Argitaratua: (2006)

Osteoblast suppression in multiple myeloma bone disease
nork: Juraj Adamik, et al.
Argitaratua: (2018-11-01)

Metformin and FTY720 Synergistically Induce Apoptosis in Multiple Myeloma Cells
nork: Yi Zhao, et al.
Argitaratua: (2018-07-01)

Systemic Dysfunction of Osteoblast Differentiation in Adipose-Derived Stem Cells from Patients with Multiple Myeloma
nork: Véronique Béréziat, et al.
Argitaratua: (2019-05-01)

EphB4 Expression in Osteoblasts is Regulated by Myeloma Cells and the Wnt Signaling Pathway.
nork: Bates, A, et al.
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5T2MM murine myeloma cells and CD138+ve human myeloma cells promote osteoclastic activity rather than osteoclast formation in vitro
nork: Mueller, G, et al.
Argitaratua: (2004)

Human Myeloma Cell Lines Induce Osteoblast Downregulation of CD99 Which Is Involved in Osteoblast Formation and Activity
nork: Angela Oranger, et al.
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Myeloma cells can promote osteoclastic activity rather than osteoclast recruitment in vitro; Evidence from the 5T2MM murine model of myeloma
nork: Mueller, G, et al.
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APOMINE (TM), a novel inhibitor of the meyalonate/isoprenoid pathway, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of the myeloma disease in vivo.
nork: Croucher, P, et al.
Argitaratua: (2002)

Natural killer cells activity against multiple myeloma cells is modulated by osteoblast-induced IL-6 and IL-10 production
nork: Christopher Uhl, et al.
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Osteoprotegerin (OPG) is a soluble decoy receptor for TRAIL/Apo2L and can inhibit TRAIL/Apo2L-induced apoptosis of human myeloma cells in vitro.
nork: Shipman, C, et al.
Argitaratua: (2002)

Myeloma cell growth suppression by osteoblast-derived extracellular vesicles: the creation of a non-permissive niche for myeloma cells by bone-forming osteoblasts
nork: SooHa Kim, et al.
Argitaratua: (2025-01-01)

Anti-tumour activity of bisphosphonates in human myeloma cells.
nork: Shipman, C, et al.
Argitaratua: (1998)

Bisphosphonates--mechanisms of action in multiple myeloma.
nork: Shipman, C, et al.
Argitaratua: (2000)

NE10790, a phosphonocarboxylate analogue of risedronate, induces human myeloma cell apoptosis in vitro
nork: Roelofs, A, et al.
Argitaratua: (2004)

Nitrogen-containing bisphosphonates induce apoptosis in human bone marrow-derived myeloma cells in vitro by inhibiting protein prenylation.
nork: Gordon, S, et al.
Argitaratua: (1999)

Regulation of bim in glucocorticoid-mediated osteoblast apoptosis.
nork: Espina, B, et al.
Argitaratua: (2008)

Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model
nork: Blomhoff Rune, et al.
Argitaratua: (2011-07-01)

Tumour cells isolated from patients with multiple myeloma express the critical osteoclastogenic factor, RANKL.
nork: Shipman, C, et al.
Argitaratua: (2000)

Osteoprotegerin is a soluble decoy receptor for tumor necrosis factor-related apoptosis-inducing ligand/Apo2 ligand and can function as a paracrine survival factor for human myeloma cells.
nork: Shipman, C, et al.
Argitaratua: (2003)

Myeloma cells can down-regulate release of osteoprotegerin (OPG) from human bone cells - A contributing factor in myeloma bone loss?
nork: Shipman, C, et al.
Argitaratua: (2002)

Ex Vivo Maintenance of Primary Human Multiple Myeloma Cells through the Optimization of the Osteoblastic Niche.
nork: Wenting Zhang, et al.
Argitaratua: (2015-01-01)

Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells
nork: Nur Mahammad, et al.
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Targeting proliferating cell nuclear antigen and its protein interactions induces apoptosis in multiple myeloma cells.
nork: Rebekka Müller, et al.
Argitaratua: (2013-01-01)