Osteoblasts protect multiple myeloma cells from T-cell-induced apoptosis

Osteoblasts protect multiple myeloma cells from T-cell-induced apoptosis

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Locklin, R, Russell, R, Croucher, P, Edwards, C
Формат:	Conference item
Хэвлэсэн:	2007

Ижил төстэй зүйлс

Cells of the bone marrow microenvironment protect myeloma cells from apoptosis induced by TRAIL but not by agonists of TRAIL death receptors.
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Agonists of TRAIL death receptors induce myeloma cell apoptosis that is not prevented by cells of the bone marrow microenvironment.
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APOMINE (TM), a novel inhibitor of the meyalonate/isoprenoid pathway, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of the myeloma disease in vivo.
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Anti-tumour activity of bisphosphonates in human myeloma cells.
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Tumour cells isolated from patients with multiple myeloma express the critical osteoclastogenic factor, RANKL.
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