Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice.

Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system associated with autoantibodies against the glial water channel protein aquaporin-4. It has recently been reported that immunoglobulin from neuromyelitis optica patients injected peripherally does not cause le...

Full description

Bibliographic Details
Main Authors: Saadoun, S, Waters, P, Bell, B, Vincent, A, Verkman, A, Papadopoulos, M
Format: Journal article
Language:English
Published: 2010