Adenovirus-mediated in utero expression of CFTR does not improve survival of CFTR knockout mice.

Gene therapy is being investigated in the treatment of lung-related aspects of the genetic disease, Cystic fibrosis (CF). Clinical studies have demonstrated CF transmembrane conductance regulator (CFTR) expression in the airways of adults with CF using a variety of gene transfer agents. In utero gen...

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Bibliographic Details
Main Authors: Davies, L, Varathalingam, A, Painter, H, Lawton, A, Sumner-Jones, S, Nunez-Alonso, G, Chan, M, Munkonge, F, Alton, E, Hyde, S, Gill, DR
Format: Journal article
Language:English
Published: 2008