FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration

Aberrant centrosome organisation with ensuing alterations of microtubule nucleation capacity enables tumour cells to proliferate and invade despite increased genomic instability. CEP192 is a key factor in the initiation process of centrosome duplication and in the control of centrosome microtubule n...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Fung, E, Richter, C, Yang, H, Schäffer, I, Fischer, R, Kessler, B, Bassermann, F, D'Angiolella, V
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: EMBO Press 2018