FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration

FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration

Aberrant centrosome organisation with ensuing alterations of microtubule nucleation capacity enables tumour cells to proliferate and invade despite increased genomic instability. CEP192 is a key factor in the initiation process of centrosome duplication and in the control of centrosome microtubule n...

Bibliografiset tiedot
Päätekijät:	Fung, E, Richter, C, Yang, H, Schäffer, I, Fischer, R, Kessler, B, Bassermann, F, D'Angiolella, V
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	EMBO Press 2018

Samankaltaisia teoksia

Fbxl13 regulates centrosome homeostasis and migration through ubiquitin mediated proteolysis
Tekijä: Fung, E
Julkaistu: (2017)

Cep192, a Novel Missing Link between the Centrosomal Core and Corona in <i>Dictyostelium</i> Amoebae
Tekijä: Valentin Pitzen, et al.
Julkaistu: (2021-09-01)

SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation.
Tekijä: D'Angiolella, V, et al.
Julkaistu: (2010)

Autophagy controls centrosome number by degrading Cep63
Tekijä: Yuichiro Watanabe, et al.
Julkaistu: (2016-11-01)

SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development
Tekijä: D'Angiolella, V, et al.
Julkaistu: (2016)

Mechanism of Centrosomal Protein 55 (CEP55) Loading Into Exosomes
Tekijä: Christian Dahlstroem, et al.
Julkaistu: (2025-02-01)

Centrosomal Protein CEP135 Regulates the Migration and Angiogenesis of Endothelial Cells in a Microtubule-Dependent Manner
Tekijä: Kun Wang, et al.
Julkaistu: (2023-11-01)

A CEP215–HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer
Tekijä: Pavithra L. Chavali, et al.
Julkaistu: (2016-03-01)

A cyclin without cyclin-dependent kinases: cyclin F controls genome stability through ubiquitin-mediated proteolysis
Tekijä: D'Angiolella, V, et al.
Julkaistu: (2012)

A cyclin without cyclin-dependent kinases: cyclin F controls genome stability through ubiquitin-mediated proteolysis.
Tekijä: D'Angiolella, V, et al.
Julkaistu: (2013)

Importance of the CEP215-pericentrin interaction for centrosome maturation during mitosis.
Tekijä: Seongjae Kim, et al.
Julkaistu: (2014-01-01)

The novel centrosomal associated protein CEP55 is present in the spindle midzone and the midbody.
Tekijä: Martinez-Garay, I, et al.
Julkaistu: (2006)

CEP250 is Required for Maintaining Centrosome Cohesion in the Germline and Fertility in Male Mice
Tekijä: Sandrine Floriot, et al.
Julkaistu: (2022-01-01)

A cyclin without cyclin-dependent kinases: Cyclin F controls genome stability through ubiquitin-mediated proteolysis
Tekijä: D'Angiolella, V, et al.
Julkaistu: (2013)

[Letter to the editor]: Commercial Cdk1 antibodies recognize the centrosomal protein Cep152
Tekijä: Gražvydas Lukinavičius, et al.
Julkaistu: (2013-09-01)

CEP192 is a novel prognostic marker and correlates with the immune microenvironment in hepatocellular carcinoma
Tekijä: Yanli Liu, et al.
Julkaistu: (2022-09-01)

USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110
Tekijä: Li, J, et al.
Julkaistu: (2013)

USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110.
Tekijä: Li, J, et al.
Julkaistu: (2013)

Stabilization of Cartwheel-less Centrioles for Duplication Requires CEP295-Mediated Centriole-to-Centrosome Conversion
Tekijä: Denisse Izquierdo, et al.
Julkaistu: (2014-08-01)

The F-box protein FBXL-5 governs vitellogenesis and lipid homeostasis in C. elegans
Tekijä: Peter C. Breen, et al.
Julkaistu: (2024-06-01)

CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2
Tekijä: Holder, J, et al.
Julkaistu: (2024)

Mosaic variegated aneuploidy syndrome with tetraploid, and predisposition to male infertility triggered by mutant CEP192
Tekijä: Jihong Guo, et al.
Julkaistu: (2024-01-01)

Effect of FBXL20 on Proliferation, Migration and Invasion of Gastric Cancer Cells
Tekijä: HAN Juan, et al.
Julkaistu: (2019-07-01)

CEP90 is required for the assembly and centrosomal accumulation of centriolar satellites, which is essential for primary cilia formation.
Tekijä: Kyeongmi Kim, et al.
Julkaistu: (2012-01-01)

CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion
Tekijä: Enrico S. Atorino, et al.
Julkaistu: (2020-02-01)

Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells
Tekijä: Yoshiharu Muto, et al.
Julkaistu: (2017-07-01)

Centrosomal Protein 55 (CEP55) Drives Immune Exclusion and Resistance to Immune Checkpoint Inhibitors in Colorectal Cancer
Tekijä: Dechen Wangmo, et al.
Julkaistu: (2024-01-01)

The centrosomal protein 83 (CEP83) regulates human pluripotent stem cell differentiation toward the kidney lineage
Tekijä: Fatma Mansour, et al.
Julkaistu: (2022-10-01)

Mitotic Maturation Compensates for Premature Centrosome Splitting and PCM Loss in Human <i>cep135</i> Knockout Cells
Tekijä: Zhenzhen Chu, et al.
Julkaistu: (2022-04-01)

Cep85 Relays Plk1 Activity to Phosphorylated Nek2A for Its Timely Activation in Centrosome Disjunction
Tekijä: Canhe Chen, et al.
Julkaistu: (2019-01-01)

Talpid3-binding centrosomal protein Cep120 is required for centriole duplication and proliferation of cerebellar granule neuron progenitors.
Tekijä: Chuanqing Wu, et al.
Julkaistu: (2014-01-01)

Epigenetic suppression of FBXL7 promotes metastasis
Tekijä: Loredana Moro, et al.
Julkaistu: (2020-11-01)

E2F1 proteolysis via SCF-cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition
Tekijä: Burdova, K, et al.
Julkaistu: (2019)

Centrosome Positioning in Migrating <i>Dictyostelium</i> Cells
Tekijä: Hellen Ishikawa-Ankerhold, et al.
Julkaistu: (2022-05-01)

Cep169, a Novel Microtubule Plus-End-Tracking Centrosomal Protein, Binds to CDK5RAP2 and Regulates Microtubule Stability.
Tekijä: Yusuke Mori, et al.
Julkaistu: (2015-01-01)

FBXL4 deficiency increases mitochondrial removal by autophagy
Tekijä: David Alsina, et al.
Julkaistu: (2020-06-01)

RL4CEP: reinforcement learning for updating CEP rules
Tekijä: Afef Mdhaffar, et al.
Julkaistu: (2025-01-01)

Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos
Tekijä: Carl Matthias, et al.
Julkaistu: (2009-03-01)

Cep63 and cep152 cooperate to ensure centriole duplication.
Tekijä: Nicola J Brown, et al.
Julkaistu: (2013-01-01)

Proteolysis of mitochondrial calpain-13 in cerebral ischemia-reperfusion injury
Tekijä: Yusaku Chukai, et al.
Julkaistu: (2024-09-01)