FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration

Aberrant centrosome organisation with ensuing alterations of microtubule nucleation capacity enables tumour cells to proliferate and invade despite increased genomic instability. CEP192 is a key factor in the initiation process of centrosome duplication and in the control of centrosome microtubule n...

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Chi tiết về thư mục
Những tác giả chính: Fung, E, Richter, C, Yang, H, Schäffer, I, Fischer, R, Kessler, B, Bassermann, F, D'Angiolella, V
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: EMBO Press 2018